Names of BRUSH scholars are underlined.

2022

Khelsea Bahr mentored by Dr. Srinand Sreevatsan. A search for unique genomic signatures among elk isolates of Mycobacterium tuberculosis variant bovis

Milady Feijoo mentored by Dr. Brian Johnson. Predicting endocrine disrupting chemicals via a human derived and metabolically competent uterotrophic assay

Evan Hughes mentored by Dr. Adam Lauver. A translational model of moxifloxacin-induced QT interval prolongation

Brush Cohort 2022

Cyrus Victor Lacuesta mentored by Drs. Jack Harkema and Jim Wagner. The Pathogenesis and persistence of lung injury in diabetic mice through repeated ozone exposure

Leah Liszak mentored by Dr. Margaret Petroff. Progesterone and estrogen: Understanding effects on neutrophil responses following Group B Streptococcus (GBS) infection in murine models

Sarah Lucas mentored by Dr. Anne Dorrance. The Effect of hypertension on carotid artery structure in male and female C57BL6 mice

Elizabeth Mateo mentored by Dr. Neera Tewari-Singh. Effect of Nrf2 activators on nitrogen mustard induced decrease in skin epidermal cell viability and proliferation

Kelly Montañez Martínez mentored by Dr. Cheryl Rockwell. Inhibition of cytokine production in dendritic cells by the Nrf2 activator, tBHQ, in female C57BL/6 mice

Jannaldo Nieves-Salva mentored by Dr. Karen Liby. The triterpenoid CDDO-methyl ester redirects polarization of human lung tumor-educated macrophages

Laura Peña Serrano mentored by Dr. Sean Crosson. Investigating the role of envelope integrity protein EipA in the ovine pathogen Brucella ovis

Caleb Ragsdale mentored by Dr. Andres Contreras. Sex and tissue location influence perivascular adipose tissue adipocyte progenitor population abundance and proximity to vasculature

Brenely Rivera mentored by Dr. Sudin Bhattacharya. How TCDD-activated AHR affects the liver circadian rhythms

Andrew Simmons mentored by Dr. Robert Quinn. Evolution of Enteroccus faecalis exposed to bile acids

Matthias Tedros mentored by Dr. Masako Morishita. Lead exposure from leaded Avgas in Michigan communities

Alanis Torres mentored by Dr. Brad Upham. The in vitro effect of per and polyfluoroalkyl substances on gap junctional intercellular communication in WB-F344 rat liver epithelial cells

James Torres mentored by Dr. John LaPres. AHR and TSPO affect the expression of Micu2 in MLE-12 cells

Kathleen Velez mentored by Dr. Norb Kaminski. Assessing the effects of Δ9-tetrahydrocannabinol (THC) on interferon alpha (IFN-𝛼)-primed interleukin-2 (IL-2) responses by primary human T cells

Taryn Vielma mentored by Dr. Andrew Olive. Variation in metabolism and surface protein expression to affect M1/M2 repolarization in alveolar-like macrophages

Jennae Whitted mentored by Dr. Rita Strakovsky. Associations of urinary phthalate metabolites with ovarian volume and differences by change in BMI since age 18

Amanda York mentored by Dr. LaPres. The Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on cholesterol biosynthesis in HepaRG cells

2021

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Ireyon Buchanna mentored by Dr. Anne Dorrance. Hypertension is associated with glucocorticoid excess and reduced glucose clearance in aged spontaneously hypertensive stroke prone rats

Andrew Decker mentored by Dr. Andres Contreras. The role of Piezo-1 in pre-adipocyte differentiation

Carmen Garcia mentored by Dr. Adam Moeser. Impact of early weaning on intestinal histamine receptor expression and localization in the piglet small intestine

Amber Hickey mentored by Dr. Robert Quinn. Self-assembly of complex polymicrobial infections

Madison Janey mentored by Dr. Cheryl Rockwell. Understanding how the food preservative tBHQ can be associated with food allergies in a juvenile mice model

Elliot Majlessi mentored by Dr. Janani Ravi. Evolution of Staphylococcal antibiotic resistance systems

2021 Student Projects

Find examples of student work here, including videos, Venn diagrams, and more.

Sierra McClain mentored by Dr. Srinand Sreevatsan. Evaluation of antibodies against SARS-CoV2 spike proteins in dogs: an analysis of exposure over the pandemic

Ebube Okpechukwu mentored by Dr. Stephanie Watts. Does Chemerin-induced contraction of non-vascular smooth muscle contribute to obesity associated diseases?

Tasha Scarlett mentored by Dr. Jack Harkema and Dr. James Wagner. Dietary omega-3 fatty acid attenuates silica-triggered autoimmune disease in adult lupus-prone mice

Jessica Suarez mentored by Dr. Adam Lauver. Evaluating basal arrhythmia incidence in a colony of telemetered non-human primates

Jackson Tucker mentored by Dr. James Luyendyk. The effect of peroxynitrite on fibrinogen binding to αMβ2 integrin expressed by THP 1 monocytic cells

2020

2020 Cohort Members

Mohamed Ahmed mentored by Dr. LaPres. The translocator protein influence on the aryl hydrocarbon receptor

Philip Calhoun mentored by Dr. Ravi. Identifying diagnostic sRNA targets in infected hosts using computational approaches

Monique Christian mentored by Drs. Mansfield, Harkema & Ewart. Defining the role of the early infant microbiome in mediating allergic outcomes associated with asthma in a mouse model

Alyssa Clements mentored by Dr. Contreras. The relationship between piezo 1 and adipogenesis

Carmen Garcia mentored by Dr. Moeser. Impact of early life stress on the activation of gastrointestinal mast cells

2020 Student Projects

Find examples of student work here, including everything from infographics to poetry.

Sierra McClain mentored by Dr Sreevatsan. SARS-CoV-2 phylogenetic evolution trimeric spike glycoprotein (S) in human and animal isolates using GSAID

Bryson Satterwhite mentored by James Luyendyk. Trichloroethylene modulates hepatic and blood gene expression in experimental primary biliary cholangitis

Dejah Wakefield mentored by Dr. Lauver. Investigating the vascular effects of clopidogrel: A review of current literature

Justin Williams mentored by Dr. Quinn. Mining public mass spectrometry data to characterize the diversity and ubiquity of P. aeruginosa specialized metabolites

2019

2019 Brush Group Formal 860

Maisah Akram, Sean Misek, Richard Neubig. Inhibition of PLK, AURK, and Tubulin in BRafi-resistant melanoma

Carmen Garcia, Shannon Manning. Role that intramammary treatment of ceftiofur has on the gut microbiome of dairy cows

Jade Gmitter, Timmy Park, Carine Holz, Ning Li. Effects of ambient air pollution on lung tumors: Does organic chemicals in particulate matter 2.5 (PM2.5) and vapor phase (vapor) influence the induction or exacerbation of lung tumors?

Taneisha Griggs, Morgan Geiger and Dana Spence. Identifying C-peptide/albumin complex receptor in healthy and type 1 diabetic subjects to reduce diabetic complications

Kimberly E. Guzman, Yining Jin and Cheryl E. Rockwell. The effect of two food additives in ovalbumin-elicited food allergy in a mouse model

2019 Student Projects

Find examples of student work here, including videos, Venn diagrams, and more.

Jazmin Johnson, Lauren Poole and James Luyendyk. Tissue transglutaminase-2 modifies fibrin(ogen) stimulated macrophage cytokine expression.

Marlin McKnight, Lauren Heine, Ashleigh Tindle, Sarah Shareef, Ryan Lewandowski, Jack Harkema and James Wagner. Contribution of innate lymphoid cells to airway inflammation and epithelial remodeling in response to endotoxin

Amari Parris, Dawn Kuszynski, Barbara Christian, Andrew Heuwagen and D. Adam Lauver. Comparing the effects of clopidogrel and DT-678 on vascular function in the middle cerebral artery

Hailey Penticoff, Michael Rizzo and Norbert Kaminski. Expression of Toll-like receptors in human primary astrocytes

Christina Straham, Ting-Chieh Yen and Anne Dorrance. The role of obesity beginning in childhood and the future development of dementia

2018

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Terry Everett, Barbara Christian, Adam Lauver. The cytotoxic effects of iodinated contrast media on renal proximal tubular epithelial cells.

Joe Faryean, James Chen, Julia Bell, Linda Mansfield. Is pain associated with nerve inflammation in Guillain-Barre Syndrome?

Cassidy Harris, Jack Harkema. The progression and persistence of ozone-induced atrophy of nasal turbinates.

Michael Mark, Malcolm Davis, Bruce Uhal. Addition of IL-10 response to hyperoxic and normoxic conditions by the mas agonist AVE-0991.

Marie Negron, Emma Darios and Stephanie Watts. Expanding our knowledge of fat: Is stretch-activated Piezo1 found in perivascular adipose tissue?

Jade Neverson, Kevin Baker, Anna Kopec, James Luyendyk. Differential activation of hepatocyte TF procoagulant activity by apoptotic and necrotic cell death.

2018 Summer Projects

Find examples of student work here, including videos, Venn diagrams, and more.

Chioma Ngene, Jacob Baker, Robert Abramovitch. Determining the function and regulation of genes selectively induced by acidic pH in the presence of glycerol.

Jaquia White, Katherine Roth, Bryan Copple. Role of annexin A2 in plasmin induced macrophage activation.

Donte Williams, Kirti Bhardwaj, Greg Swain. Diamond microelectrodes for electroanalytical measurements of catechol amine neurotransmitters and metabolites.

2017

Recent Projects Group Photo

Joe Faryean, Alex Ethridge, and Linda S. Mansfield. Evidence of Guillain-Barré Syndrome-like peripheral nerve lesions in NOD mice transplanted with human intestinal microbiota and infected with Campylobacter jejuni.

Romel Holmes, Bruce Uhal. The MAS activator AVE 0991 inhibits meconium-induced apoptosis in human lung epithelial cells.

Nicole Insko, Andrew Cwiek, Arantzazu Eiquren-Fernandez, Ning Li. Ambient vapor-phase pollutants suppress the innate immune response of dendritic cells.

Tyshana Johnson, Naiomy D. Rios-Arce, Laura R. McCabe, Narayanan Parameswaran. Intestinal inflammatory responses to antibiotics in male and female RAG-knockout mice.

Lindsey Lund, Daniel Claiborne, Julia Bell, Linda Mansfield, Susan Ewart. Examining the influence of the microbiome on asthma in a mouse model.

Janae Lyttle, Stephanie Watts. The identification of transglutaminases in perivascular adipose tissue.

Sharon-Rose Nartey, Huiqing Zheng, Robert B. Abramovitch. Structure and function studies of DosS, DosT, DosSG117L, and DosE87L with Artemisinin-like compounds and synthetic endoperoxides.

David Nava, Peter Dornbos, John LaPres. Use of a population-guided approach to identify novel genetic modulators of TCDD-induced liver toxicity.

James Sykes, Ananth Kumar Kammala and Hariharan Subramanian. Identification of plant-derived compounds to treat mast cell-mediated allergic disorders.

Eden Teshome, E. Eldridge, A. Freeland, R. Lewandowski, P. Akbari, J. Wagner, and J. Harkema. Progression and persistence of eosinophilic rhinitis in ozone-exposed F344 rats.